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5 Clinical application of probiotics The clinical utility of probiotics in UC is primarily as an adjunct to standard therapy, with evidence of synergistic benefit in selected contexts

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Furthermore, when Cnd1-Pmc4 double depletion was compared to Cnd1 single depletion, we observed that genomic contacts within approximately 800 kb were increased, suggesting that mediator can inhibit genomic contacts within this range (Supplementary Fig